Dr. Haneen AlBoosta, Consultant General and Endocrine Surgeon in Bahrain

Dr. Haneen AlBoosta — Consultant General, Endocrine & Laparoscopic Surgeon

Adrenal Mass Assessment and Adrenal Surgery in Bahrain

Dr. Haneen AlBoosta — Consultant General, Endocrine & Laparoscopic Surgeon in Bahrain

Most adrenal masses are found by chance on a scan of the abdomen, and the majority are benign and non-functioning. Assessment answers two questions: does the mass produce excess hormones, and are its size and imaging features reassuring? When both answers are reassuring, monitoring is usually enough. Adrenal surgery is considered for hormonally active tumours, larger or suspicious lesions, or a mass that grows on follow-up.

What do the adrenal glands do?

You have one adrenal gland above each kidney. They produce cortisol, aldosterone and adrenaline — hormones that influence the body's stress response, salt and water balance, and blood pressure.

A lump in an adrenal gland is common and is usually discovered incidentally during a CT scan carried out for another reason. Finding one does not mean cancer and does not mean an operation is needed; it means a structured assessment is needed.

Functioning and non-functioning adrenal lesions

  • Non-functioning adrenal adenoma: a benign lesion producing no excess hormone.
  • Adrenal incidentaloma: any adrenal mass found unexpectedly on imaging.
  • Primary aldosteronism: excess aldosterone, often with high blood pressure and low potassium.
  • Cushing syndrome: excess cortisol, which may cause weight gain, high blood pressure and high blood sugar.
  • Phaeochromocytoma: a tumour releasing adrenaline-type hormones, causing episodes of high blood pressure, palpitations, sweating and headache.

Hormonal work-up and imaging

  • Review of the CT or MRI, including lesion size, density and growth over time.
  • Blood pressure, potassium, current medications and symptom review.
  • Cortisol testing with a suppression test where indicated.
  • Aldosterone-to-renin ratio when there is hypertension or low potassium.
  • Plasma or urinary metanephrines to exclude a phaeochromocytoma.

When observation is appropriate

  • A small lesion with benign imaging characteristics.
  • No hormone excess on biochemical testing.
  • No symptoms suggesting a functioning tumour.
  • A stable size on repeat imaging over the follow-up period.

When adrenal surgery is considered

Adrenalectomy is discussed when the mass is hormonally active, when it is large or has features on imaging that are not reassuring, when it grows during follow-up, or when a phaeochromocytoma is confirmed.

Where the case is suitable, the operation can often be performed laparoscopically, with small incisions and a quicker recovery. Larger or more complex lesions may require a different surgical approach.

Preparation before surgery and follow-up

Preoperative endocrine preparation is essential rather than routine. In phaeochromocytoma and primary aldosteronism, specific medication is started beforehand to control blood pressure and correct electrolytes, which makes the operation safer.

After surgery, blood pressure and hormone levels are monitored. Depending on the type of lesion, some patients need temporary hormone replacement while the remaining gland recovers.

Frequently Asked Questions

Does every adrenal mass need surgery?

No. Many adrenal masses are small, non-functioning and benign on imaging, and are safely monitored with repeat scans and blood tests.

What is an adrenal incidentaloma?

An adrenal mass discovered unexpectedly on a scan done for another reason. The first steps are checking whether it produces hormones and whether its imaging features are reassuring.

How do doctors know whether an adrenal mass produces hormones?

Through targeted tests: cortisol and suppression testing, the aldosterone-to-renin ratio, and plasma or urinary metanephrines, alongside blood pressure and potassium.

What is a phaeochromocytoma?

An adrenal tumour that releases adrenaline-type hormones. It can cause episodes of high blood pressure, palpitations, sweating and headache, and needs careful medical preparation before any operation.

Does every adrenal tumour mean cancer?

No. The large majority are benign. Malignant adrenal tumours are uncommon, and the risk is judged from size, imaging characteristics and medical history.

When is adrenalectomy recommended?

For hormonally active tumours, confirmed phaeochromocytoma, larger or suspicious lesions, or a mass that clearly grows during follow-up.

What tests are needed before adrenal surgery?

A complete hormonal work-up, up-to-date CT or MRI, assessment of blood pressure and electrolytes, and specific medical preparation for functioning tumours.

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Medical Review

Reviewed by Dr. Haneen AlBoosta, Consultant General & Endocrine Surgeon. This page is updated periodically to remain consistent with current medical references and international guidelines. It is intended for general education and does not replace an individual medical consultation, examination or treatment plan.

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